1. 1

    Do not rely on random measures of circadian hormones for diagnostic purposes

  2. 2

    Do not rely solely on bone age measurement for assessing growth in young children with short stature under 2 years of age 

  3. 3

    Do not routinely measure insulin-like growth factor binding protein 3 (IGFBP-3) for workup and diagnosis of childhood short stature

  4. 4

    Do not initiate gonadotropin-releasing hormone (GnRH) analogue treatment in children outside of central precocious puberty, for the target outcome of delaying puberty and improving final adult height   

  5. 5

    Do not routinely prescribe aromatase inhibitors to promote growth in children with short stature